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Space Station Science: Biological Research

Each month, we highlight a different research topic on the International Space Station. In August, our focus is biological research. Learning how spaceflight affects living organisms will help us understand potential health risks related to humans on long duration missions, including our journey to Mars.

Cells, microbes, animals and plants are affected by microgravity, and studying the processes involved in adaptation to spaceflight increases our fundamental understanding of biological processes on Earth. Results on Earth from biological research in space include the development of new medications, improved agriculture, advancements in tissue engineering and regeneration, and more. 

Take a look at a few of the biological research experiments performed on space station:

Biomolecule Sequencer

Living organisms contain DNA, and sequencing DNA is a powerful way to understand how they respond to changing environments. The Biomolecule Sequencer experiment hopes to demonstrate (for the first time) that DNA sequencing is feasible in an orbiting spacecraft. Why? A space-based DNA sequencer could identify microbes, diagnose diseases and understand crew member health, and potentially help detect DNA- based life elsewhere in the solar system.

Ant-stronauts

Yes, ant-stronauts…as in ants in space. These types of studies provide insights into how ants answer collective search problems. Watching how the colony adapts as a unit in the quest for resources in extreme environments, like space, provides data that can be used to build algorithms with varied applications. Understanding how ants search in different conditions could have applications for robotics.

TAGES

The TAGES experiment (Transgenic Arabidopsis Gene Expression System) looks to see how microgravity impacts the growth of plant roots. Fluorescent markers placed on the plant’s genes allow scientists to study root development of Arabidopsis (a cress plant) grown on the space station. Evidence shows that directional light in microgravity skews root growth to the right, rather than straight down from the light source. Root growth patters on station mimic that of plants grown at at 45% degree angle on Earth. Space flight appears to slow the rate of the plant’s early growth as well.

Heart Cells

Spaceflight can cause a suite of negative health effects, which become more problematic as crew members stay in orbit for long periods of time. Effects of Microgravity on Stem Cell-Derived Cardiomycytes (Heart Cells) studies the human heart, specifically how heart muscle tissue contracts, grows and changes in microgravity. Understanding how heart muscle cells change in space improves efforts for studying disease, screening drugs and conducting cell replacement therapy for future space missions.

Medaka Fish

Chew on these results…Jaw bones of Japanese Medaka fish in microgravity show decreased mineral density and increased volume of osteoclasts, cells that break down bone tissue. Results from this study improve our understanding of the mechanisms behind bone density and organ tissue changes in space.

These experiments, and many others, emphasize the importance of biological research on the space station. Understanding the potential health effects for crew members in microgravity will help us develop preventatives and countermeasures.

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Solar System: 5 Things to Know This Week

Our solar system is huge, so let us break it down for you. Here are 5 things to know this week:

1. It’s Lunacy, Whether by Day or Night

What’s Up in the night sky during November? See all the phases of the moon by day and by night, and learn how to look for the Apollo landing sites. Just after sunset on November 13 and 14, look near the setting sun in the western sky to see the moon as a slender crescent. For more, catch the latest edition of the monthly “What’s Up” Tumblr breakdown.

2. Answer to Longstanding Mars Mystery is Blowin’  in the Wind

What transformed Mars from a warm and wet environment, one that might have supported surface life, to the cold, arid planet it is today? Data from our Mars Atmosphere and Volatile Evolution (MAVEN) mission pins much of the blame on the sun. Streams of charged solar particles crash against the Martian atmosphere, and without much of a magnetic field there to deflect the onslaught, over time the solar wind has stripped the air away.

3. Orbital Maneuvers in the Dark

The New Horizons mission team has set a new record. They recently performed the last in a series of trajectory changes that set the spacecraft on a course for an encounter with a Kuiper Belt object in January 2019. The Kuiper Belt consists of small bodies that orbit the sun a billion miles or more beyond Pluto. These latest course maneuvers were the most distant trajectory corrections ever performed by any spacecraft.

4. Visit Venus (But Not Really — You’d Fry)

Mars isn’t the only available destination. You can visit all the planets, moons and small worlds of the solar system anytime, right from your computer or handheld device. Just peruse our planets page, where you’ll find everything from basic facts about each body to the latest pictures and discoveries. Visit Venus HERE.

5. Titan Then and Now

Nov. 12 marks the 35th anniversary of Voyager 1’s Saturn flyby in 1980. Voyager saw Saturn’s enshrouded, planet-sized moon Titan as a featureless ball. In recent years, the Cassini mission haas revealed Titan in detail as a complex world. The spacecraft has peered beneath its clouds, and even delivered a probe to its encounter, which will include infrared scans, as well as using visible light cameras to look for methane clouds in the atmosphere.

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The As, Gs, Cs and Ts of the Space Station: First In-Space Microbe Identification

Being able to identify microbes in real-time aboard the International Space Station, without having to send them back to Earth for identification first, would be totally amazing for the world of microbiology and space exploration.

The Genes in Space 3 team turned that possibility into a reality this year, when it completed the first-ever sample-to-sequence process entirely aboard the space station.

The ability to identify microbes in space could aid in the ability to diagnose and treat astronauts in real time, as well as assisting in the identification of life on other planets. It could also benefit other experiments aboard the space station.

HELPFUL SCIENCE HINT: Identifying microbes involves isolating the DNA of samples, and then amplifying – or making lots and lots (and LOTS) of copies - of that DNA that can then be sequenced, or identified.  

As part of regular monitoring, petri plates were touched to various surfaces of the space station. NASA astronaut Peggy Whitson transferred cells from growing bacterial colonies on those plates into miniature test tubes, something that had never been done before in space (first OMG moment!).

Once the cells were successfully collected, it was time to isolate the DNA and prepare it for sequencing, enabling the identification of the unknown organisms – another first for space microbiology.

Enter Hurricane Harvey. *thunder booms*

“We started hearing the reports of Hurricane Harvey the week in between Peggy performing the first part of collecting the sample and gearing up for the actual sequencing,” said Sarah Wallace, the project’s primary investigator.

When our Johnson Space Center (JSC) in Houston became inaccessible due hurricane conditions, Marshall Space Flight Center’s Payload Operations Integration Center in Huntsville, Alabama worked to connect Wallace to Whitson using Wallace’s personal cell phone.

With a hurricane wreaking havoc outside, Wallace and Whitson set out to make history.

The data were downlinked to the team in Houston for analysis and identification.

“Once we actually got the data on the ground we were able to turn it around and start analyzing it,” said Aaron Burton, the project’s co-investigator. “You get all these squiggle plots and you have to turn that into As, Gs, Cs and Ts.”

Those As, Gs, Cs and Ts are more than just a nerdy alphabet – they are Adenine, Guanine, Cytosine and Thymine – the four bases that make up each strand of DNA and can tell you what organism the strand of DNA came from. 

“Right away, we saw one microorganism pop up, and then a second one, and they were things that we find all the time on the space station,” said Wallace. “The validation of these results would be when we got the sample back to test on Earth.”

Soon after, the samples returned to Earth aboard the Soyuz spacecraft, along with Whitson.

With the samples now in the team’s JSC lab, tests were completed in ground labs to confirm the findings from the space station. They ran the tests again and again, and then once more, to confirm accuracy. Each time, the results were exactly the same on the ground as in orbit. (second OMG moment!)

“We did it. Everything worked perfectly,” said Sarah Stahl, microbiologist.

This capability could change future space exploration.

“As a microbiologist,” said Wallace, “My goal is really so that when we go and we move beyond ISS and we’re headed towards Mars or the moon or wherever we are headed to, we have a process that the crew can have that great understanding of the environment, based on molecular technology.”

For more information, follow @ISS_Research. 

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NASA’s New Planet Hunter Reveals a Sky Full of Stars

NASA’s newest planet-hunting satellite — the Transiting Exoplanet Survey Satellite, or TESS for short — has just released its first science image using all of its cameras to capture a huge swath of the sky! TESS is NASA’s next step in the search for planets outside our solar system, called exoplanets.

This spectacular image, the first released using all four of TESS’ cameras, shows the satellite’s full field of view. It captures parts of a dozen constellations, from Capricornus (the Sea Goat) to Pictor (the Painter’s Easel) — though it might be hard to find familiar constellations among all these stars! The image even includes the Large and Small Magellanic Clouds, our galaxy’s two largest companion galaxies.

The science community calls this image “first light,” but don’t let that fool you — TESS has been seeing light since it launched in April. A first light image like this is released to show off the first science-quality image taken after a mission starts collecting science data, highlighting a spacecraft’s capabilities.

TESS has been busy since it launched from NASA’s Kennedy Space Center in Cape Canaveral, Florida. First TESS needed to get into position, which required a push from the Moon. After nearly a month in space, the satellite passed about 5,000 miles from the Moon, whose gravity gave it the boost it needed to get into a special orbit that will keep it stable and maximize its view of the sky.

During those first few weeks, we also got a sneak peek of the sky through one of TESS’s four cameras. This test image captured over 200,000 stars in just two seconds! The spacecraft was pointed toward the constellation Centaurus when it snapped this picture. The bright star Beta Centauri is visible at the lower left edge, and the edge of the Coalsack Nebula is in the right upper corner.

After settling into orbit, scientists ran a number of checks on TESS, including testing its ability to collect a set of stable images over a prolonged period of time. TESS not only proved its ability to perform this task, it also got a surprise! A comet named C/2018 N1 passed through TESS’s cameras for about 17 hours in July.

The images show a treasure trove of cosmic curiosities. There are some stars whose brightness changes over time and asteroids visible as small moving white dots. You can even see an arc of stray light from Mars, which is located outside the image, moving across the screen.

Now that TESS has settled into orbit and has been thoroughly tested, it’s digging into its main mission of finding planets around other stars. How will it spot something as tiny and faint as a planet trillions of miles away? The trick is to look at the star!

So far, most of the exoplanets we’ve found were detected by looking for tiny dips in the brightness of their host stars. These dips are caused by the planet passing between us and its star – an event called a transit. Over its first two years, TESS will stare at 200,000 of the nearest and brightest stars in the sky to look for transits to identify stars with planets.

TESS will be building on the legacy of NASA’s Kepler spacecraft, which also used transits to find exoplanets. TESS’s target stars are about 10 times closer than Kepler’s, so they’ll tend to be brighter. Because they're closer and brighter, TESS’s target stars will be ideal candidates for follow-up studies with current and future observatories.

TESS is challenging over 200,000 of our stellar neighbors to a staring contest! Who knows what new amazing planets we’ll find?

The TESS mission is led by MIT and came together with the help of many different partners. You can keep up with the latest from the TESS mission by following mission updates.

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Here’s What You Need to Know About Near-Earth Objects

Our solar system is littered with asteroids and comets, and sometimes they get a little close to Earth. But no need to worry! This happens all the time. When an asteroid or comet could come close to our planet, it’s known as a near-Earth object – aka NEO.

But how close is “close”?

A near-Earth object is defined as an object that could pass by our Earth within 30 million miles. We begin to keep close watch on objects that could pass within 5 million miles of our planet.

To put that into perspective, our Moon is only 238,900 miles away.

However unlikely an impact is, we want to know about all near-Earth objects. Our Planetary Defense Coordination Office maintains watch for asteroids and comets coming close to Earth. Along with our partners, we discover, catalog and characterize these bodies.

But what if one of these objects posed a threat?

We want to be prepared. That is why we are working on several deflection techniques and technologies to help protect our planet.

So next time that you hear of an asteroid passing “close” to Earth, know that it’s just one of many that we are tracking.

Here are 10 more things you should know about Planetary Defense.

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What was your first thought when you first saw earth from space? And what realizations did you have?

Spacewalk Friday: Installing a New "Parking Spot" on Station

This Friday, Aug. 19, two U.S. astronauts will install a new gateway for American commercial crew spacecraft at the International Space Station. 

Commercial crew flights from Florida’s Space Coast to the International Space Station will restore America’s human spaceflight launch capability and increase the time U.S. crews can dedicate to scientific research.

The adapter being installed (imaged below) was launched on a SpaceX Dragon cargo spacecraft and arrived on orbit July 20. This ring is known as an International Docking Adapter, or IDA, and its main purpose is to provide a port for spacecraft bringing astronauts to the station in the future. Outfitted with a host of sensors and systems, the adapter is built so spacecraft systems can automatically perform all the steps of arrival and docking with the station without input from the astronauts. 

NASA astronauts Jeff Williams and Kate Rubins will perform the spacewalk to install the equipment this Friday, Aug. 19. This will be the fourth spacewalk in Williams’ career and the first for Rubins.

Four previous spacewalks...like the one below...helped set the stage for installation of this docking adapter. During those previous spacewalks, other crew members laid hundreds of feet of power and data cables outside the space station. 

On Wednesday, the robotics team using the Canadarm2 and its attached “Dextre” manipulator, will reach into the SpaceX Dragon trunk and pull out the docking adapter and position it for Friday’s spacewalk activities.

The morning of the spacewalk, while the astronauts are getting suited up, the robotic arm will position the docking adaptor near the port so that it will be ready for installation.

The two astronauts will venture outside the space station to install the first International Docking Adapter (IDA). This new adapter port will provide a parking space for U.S. Commercial Crew vehicles.

Watch LIVE!

Coverage of the spacewalk begins at 6:30 a.m. EDT on Friday, Aug. 19; with the spacewalk scheduled to begin at 8:05 a.m. EDT. Stream live online HERE. 

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Help Explore Your Own Solar Neighborhood

We’re always making amazing discoveries about the farthest reaches of our universe, but there’s also plenty of unexplored territory much closer to home.

Our “Backyard Worlds: Planet 9” is a citizen science project that asks curious people like you — yes, you there! — to help us spot objects in the area around our own solar system like brown dwarfs. You could even help us figure out if our solar system hosts a mysterious Planet 9!

In 2009, we launched the Wide-field Infrared Survey Explorer (WISE). Infrared radiation is a form of light that humans can’t see, but WISE could. It scans the sky for infrared light, looking for galaxies, stars and asteroids. Later on, scientists started using it to search for near-Earth objects (NEOWISE) like comets and asteroids.

These searches have already turned up so much data that researchers have trouble hunting through all of it. They can’t do it on their own. That’s why we asked everyone to chip in. If you join Backyard Worlds: Planet 9, you’ll learn how to look at noisy images of space and spot previously unidentified objects. 

You’ll figure out how to tell the difference between real objects, like planets and stars, and artifacts. Artifacts are blurry blobs of light that got scattered around in WISE’s instruments while it was looking at the sky. These “optical ghosts” sometimes look like real objects.

Why can’t we use computers to do this, you ask? Well, computers are good at lots of things, like crunching numbers. But when it comes to recognizing when something’s a ghostly artifact and when it’s a real object, humans beat software all the time. After some practice, you’ll be able to recognize which objects are real and which aren’t just by watching them move!

One of the things our citizen scientists look for are brown dwarfs, which are balls of gas too big to be planets and too small to be stars. These objects are some of our nearest neighbors, and scientists think there’s probably a bunch of them floating around nearby, we just haven’t been able to find all of them yet. 

But since Backyard Worlds launched on February 15, 2016, our volunteers have spotted 432 candidate brown dwarfs. We’ve been able to follow up 20 of these with ground-based telescopes so far, and 17 have turned out to be real!

Image Credit: Ryan Trainor, Franklin and Marshall College

How do we know for sure that we’ve spotted actual, bona fide, authentic brown dwarfs? Well, like with any discovery in science, we followed up with more observation. Our team gets time on ground-based observatories like the InfraRed Telescope Facility in Hawaii, the Magellan Telescope in Chile (pictured above) and the Apache Point Observatory in New Mexico and takes a closer look at our candidates. And sure enough, our participants found 17 brown dwarfs!

But we’re not done! There’s still lots of data to go through. In particular, we want your help looking for a potential addition to our solar system’s census: Planet 9. Some scientists think it’s circling somewhere out there past Pluto. No one has seen anything yet, but it could be you! Or drop by and contribute to our other citizen science projects like Disk Detective.

Congratulations to the citizen scientists who spotted these 17 brown dwarfs: Dan Caselden, Rosa Castro, Guillaume Colin, Sam Deen, Bob Fletcher, Sam Goodman, Les Hamlet, Khasan Mokaev, Jörg Schümann and Tamara Stajic.

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Celebrating the Earth (Off the Earth!)

To find the perfect perch for Earth observation research, just look up – about 240 miles up. The International Space Station serves as an optimal platform for studying our dynamic planet, where spectacular views support science.

With currently active instruments and facilities like High Definition Earth Viewing, Crew Earth Observations, Lightning Imaging Sensor, SAGE-III and Meteor, researchers on the ground are able to use the station’s unique (and useful!) vantage point to track Earth’s weather patterns, obtain images documenting changes on the planet’s surface, understand the origin of meteors falling towards Earth, and better understand the atmosphere.

The space station’s 90-minute orbit allows it to cover 90% of the Earth’s populated surfaces. That means we are able to study A LOT of that big blue marble.

Let’s talk a little about how the space station serves as a platform for Earth observation:

Each day, as the space station passes over regions of the Earth, crew members photograph the area below as a part of the Crew Earth Observations Facility investigation, one of the longest-running experiments on the orbiting laboratory. Crew members are able to photograph large-scale weather events like the recent Hurricane Harvey from the space station’s Cupola. These little science postcards from space can be used by researchers and the public to learn more about our home planet.

Want to see a picture of your hometown from space? Search for it in the Gateway to Astronaut Photography of Earth (GAPE).

The High Definition Earth Viewing (HDEV) experiment streams live video of Earth for online viewing. This investigation not only provides hours and hours of footage of the Earth below, but also demonstrates how the technology holds up against the harsh environment of space. High school students helped design some of the cameras' components, through the High Schools United with NASA to Create Hardware (HUNCH) program, and student teams perform most of the HDEV operation. (Whoa! Check out HUNCH and STEM on Station for more opportunities for student involvement!)

Useful for weather forecasting, hurricane monitoring, and observations of large-scale climate phenomena such as El Niño, RapidScat used radar pulses reflected off the ocean to measure wind speed and direction over the ocean.

RapidScat completed its successful two-year mission, outlasting its original decommission date before suffering a power loss. Although RapidScat is no longer transmitting data back to Earth, the station hosts many other Earth-observation tools the Cyclone Intensity Measurements from the ISS (CyMISS) an experiment that seeks to develop detailed information on tropical storm structure to better estimate storm intensity, which will help government agencies to better prepare communities for impending natural disasters; and the Cloud-Aerosol Transport System (CATS), a previously-flown lidar instrument which measured atmospheric profiles of aerosols and clouds to better understand their properties and interactions, as well as provided data useful to improving climate change models.

Learn more about RapidScat’s mission conclusion HERE! Take a look at CATS mission data HERE!

Watch more inspiring videos and learn about how we’re capturing the beauty of Earth HERE.

Crew members are able to photograph large-scale weather events like the recent Hurricane Harvey from the space station’s Cupola. These little science postcards from space can be used by researchers and the public to learn more about our home planet.

Plants in space!

Future long-duration missions into the solar system will require a fresh food supply to supplement crew diets, which means growing crops in space. Growing food in such a harsh environment also teaches us a little bit about growing in harsh environments here on Earth.

Here are a few plant-based investigations currently happening aboard the orbiting laboratory:

Veggie is a chamber on the space station that helps scientists grow, harvest and study different space crops. This experiment is called VEG-03D and they’ve been able to grow six rounds of crops so far.

SpaceX's 13th Commercial Resupply vehicle carried many valuable items to the orbiting laboratory, including Plant Gravity Perception, an investigation that uses the European Modular Cultivation System (EMCS) to simulate gravity to help plants grow its roots downward, and shoots upwards. The shoots need to face upwards, towards the light, so they can absorb sunlight and nutrients. Without this, plants wouldn’t know which way to grow. Yikes!

Learn more about Plant Gravity Perception HERE!

The Advanced Plant Habitat is a large chamber that supports commercial and fundamental plant research for at least one year of continuous use. A great feature to this habitat is that the astronauts can view the plant’s progress through a window on the door.

Whether astronauts are taking pictures of the planet or growing crops in space, all science aboard the space station plants seeds for a better life on Earth. Biology investigations directly grow our knowledge of agricultural techniques for harsh environments and imagery from space can give us a clearer idea of our planet’s health and emerging weather patterns.

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You’re Always Surrounded by Neutrinos!

This second, as you’re reading these words, trillions of tiny particles are hurtling toward you! No, you don’t need to brace yourself. They’re passing through you right now. And now. And now. These particles are called neutrinos, and they’re both everywhere in the cosmos and also extremely hard to find.

Neutrinos are fundamental particles, like electrons, so they can’t be broken down into smaller parts. They also outnumber all the atoms in the universe. (Atoms are made up of electrons, protons, and neutrons. Protons and neutrons are made of quarks … which maybe we’ll talk about another time.) The only thing that outnumbers neutrinos are all the light waves left over from the birth of the universe! 

Credit: Photo courtesy of the Pauli Archive, CERN

Physicist Wolfgang Pauli proposed the existence of the neutrino, nearly a century ago. Enrico Fermi coined the name, which means “little neutral one” in Italian, because these particles have no electrical charge and nearly no mass.

Despite how many there are, neutrinos are really hard to study. They travel at almost the speed of light and rarely interact with other matter. Out of the universe’s four forces, ghostly neutrinos are only affected by gravity and the weak force. The weak force is about 10,000 times weaker than the electromagnetic force, which affects electrically charged particles. Because neutrinos carry no charge, move almost as fast as light, and don’t interact easily with other matter, they can escape some really bizarre and extreme places where even light might struggle getting out – like dying stars!

Through the weak force, neutrinos interact with other tiny fundamental particles: electrons, muons [mew-ons], and taus [rhymes with “ow”]. (These other particles are also really cool, but for right now, you just need to know that they’re there.) Scientists actually never detect neutrinos directly. Instead they find signals from these other particles. So they named the three types, or flavors, of neutrinos after them.

Neutrinos are made up of each of these three flavors, but cycle between them as they travel. Imagine going to the store to buy rocky road ice cream, which is made of chocolate ice cream, nuts, and marshmallows. When you get home, you find that it’s suddenly mostly marshmallows. Then in your bowl it’s mostly nuts. But when you take a bite, it’s just chocolate! That’s a little bit like what happens to neutrinos as they zoom through the cosmos.

Credit: CERN

On Earth, neutrinos are produced when unstable atoms decay, which happens in the planet’s core and nuclear reactors. (The first-ever neutrino detection happened in a nuclear reactor in 1955!) They’re also created by particle accelerators and high-speed particle collisions in the atmosphere. (Also, interestingly, the potassium in a banana emits neutrinos – but no worries, bananas are perfectly safe to eat!)

Most of the neutrinos around Earth come from the Sun – about 65 billion every second for every square centimeter. These are produced in the Sun’s core where the immense pressure squeezes together hydrogen to produce helium. This process, called nuclear fusion, creates the energy that makes the Sun shine, as well as neutrinos.

The first neutrinos scientists detected from outside the Milky Way were from SN 1987A, a supernova that occurred only 168,000 light-years away in a neighboring galaxy called the Large Magellanic Cloud. (That makes it one of the closest supernovae scientists have observed.) The light from this explosion reached us in 1987, so it was the first supernova modern astronomers were able to study in detail. The neutrinos actually arrived a few hours before the light from the explosion because of the forces we talked about earlier. The particles escape the star’s core before any of the other effects of the collapse ripple to the surface. Then they travel in pretty much a straight line – all because they don’t interact with other matter very much.

Credit: Martin Wolf, IceCube/NSF

How do we detect particles that are so tiny and fast – especially when they rarely interact with other matter? Well, the National Science Foundation decided to bury a bunch of detectors in a cubic kilometer of Antarctic ice to create the IceCube Neutrino Observatory. The neutrinos interact with other particles in the ice through the weak force and turn into muons, electrons, and taus. The new particles gain the neutrinos’ speed and actually travel faster than light in the ice, which produces a particular kind of radiation IceCube can detect. (Although they would still be slower than light in the vacuum of space.)

In 2013, IceCube first detected high-energy neutrinos, which have energies up to 1,000 times greater than those produced by Earth’s most powerful particle collider. But scientists were puzzled about where exactly these particles came from. Then, in 2017, IceCube detected a high-energy neutrino from a monster black hole powering a high-speed particle jet at a galaxy’s center billions of light-years away. It was accompanied by a flash of gamma rays, the highest energy form of light.

But particle jets aren’t the only place we can find these particles. Scientists recently announced that another high-energy neutrino came from a black hole shredding an unlucky star that strayed too close. The event didn’t produce the neutrino when or how scientists expected, though, so they’ve still got a lot to learn about these mysterious particles!

Keep up with other exciting announcements about our universe by following NASA Universe on Twitter and Facebook.

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