What Can We Learn From The Universe’s Baby Picture?

Small Tissue Chips in Space a Big Leap Forward for Research

Tissue chips, thumb-drive sized devices that contain human cells in a 3D matrix, represent a giant leap in science.

They can test cells’ response to:

•stresses

•drugs

•genetic changes

The Tissue Chips in Space initiative seeks to better understand the role of microgravity on human health and disease and to translate that understanding to improved human health on Earth.

This series of investigations to test tissue chips in microgravity aboard the International Space Station is planned through a collaboration between the National Center for Advancing Translational Sciences (NCATS) at the National Institutes for Health (NIH) and the National Laboratory in partnership with NASA.

Many of the changes in the human body caused by microgravity resemble the onset and progression of diseases associated with aging on Earth, but in space, changes occur much faster. Scientists may be able to use tissue chips in space to model changes that take months or years to happen on Earth.

A tissue chip needs three properties, according to Lucie Low, scientific program manager at NCATS. “It has to be 3D,” she explained. “It must have multiple different types of cells, and it must have microfluidic channels. Essentially, you get a functional unit of what human tissues are like, outside of the body,” said Low.

As accurate models of the structure and function of human organs, tissue chips provide a model for predicting whether a drug, vaccine or biologic agent is safe in humans more quickly and effectively than current methods.

This first phase of Tissue Chips in Space includes five investigations. An investigation of immune system aging is planned for launch on the SpaceX CRS-16 flight, scheduled for mid-November. The other four, scheduled to launch on subsequent flights, include lung host defense, the blood-brain barrier, musculoskeletal disease and kidney function. This phase tests the effects of microgravity on the tissue chips and demonstrates the capability of the automated system.

All five investigations make a second flight about 18 months later to confirm use of the model, such as testing potential drugs on the particular organs. Four more projects are scheduled for launch in summer 2020, including two on engineered heart tissue to understand cardiovascular health, one on muscle wasting and another on gut inflammation.

Ultimately, the technology could allow astronauts going into space to take along personalized chips that could be used to monitor changes in their bodies and to test possible countermeasures and therapies. That would be a major leap forward in keeping astronauts healthy on missions to deep space!

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

Resupply Mission Brings Mealworms and Mustard Seeds to Space Station

Orbital ATK will launch its Cygnus cargo spacecraft to the International Space Station on November 11, 2017 from Wallops Flight Facility in Virginia. It will be packed with cargo and scientific experiments for the six humans currently living and working on the orbiting laboratory.

The cargo spacecraft is named the S.S. Gene Cernan after former NASA astronaut Eugene Cernan, who is the last man to have walked on the moon.

Here are some of the really neat science and research experiments that will be delivered to the station: 

What’s Microgravity Got to do with Bacterial Antibiotics?

Antibiotic resistance could pose a danger to astronauts, especially since microgravity has been shown to weaken human immune response. E. coli AntiMicrobial Satellite (EcAMSat) will study microgravity’s effect on bacterial antibiotic resistance.

Results from this experiment could help us determine appropriate antibiotic dosages to protect astronaut health during long-duration human spaceflight and help us understand how antibiotic effectiveness may change as a function of stress on Earth.

Laser Beams…Not on Sharks…But on a CubeSat

Traditional laser communication systems use transmitters that are far too large for small spacecraft. The Optical Communication Sensor Demonstration (OCSD) tests the functionality of laser-based communications using CubeSats that provide a compact version of the technology.

Results from OCSD could lead to improved GPS and other satellite networks on Earth and a better understanding of laser communication between small satellites in low-Earth orbit.

This Hybrid Solar Antenna Could Make Space Communication Even Better 

As space exploration increases, so will the need for improved power and communication technologies. The Integrated Solar Array and Reflectarray Antenna (ISARA), a hybrid power and communication solar antenna that can send and receive messages, tests the use of this technology in CubeSat-based environmental monitoring. 

ISARA may provide a solution for sending and receiving information to and from faraway destinations, both on Earth and in space. 

More Plants in Space!  

Ready for a mouthful…The Biological Nitrogen Fixation in Microgravity via Rhizobium-Legume Symbiosis…aka the Biological Nitrogen Fixation experiment, will examine how low-gravity conditions affect the nitrogen fixation process of the Microclover legume (a plant in the pea family). Nitrogen fixation is a process where nitrogen in the atmosphere is converted into ammonia. This crucial element of any ecosystem is also a natural fertilizer that is necessary for most types of plant growth.

This experiment could tell us about the space viability of the legume’s ability to use and recycle nutrients and give researchers a better understanding of this plant’s potential uses on Earth.

What Happens When Mealworms Live in Space?

Mealworms are high in nutrients and one of the most popular sources of alternative protein in developing countries. The Effects of Microgravity on the Life Cycle of Tenebrio Molitor (Tenebrio Molitor) investigation studies how the microgravity environment affects the mealworm life cycle.

In addition to alternative protein research, this investigation will provide information about animal growth under unique conditions.

Mustard Seeds in Microgravity 

The Life Cycle of Arabidopsis thaliana in Microgravity experiment studies the formation and functionality of the Arabidopsis thaliana, a mustard plant with a genome that is fully mapped, in microgravity conditions.

The results from this investigation could contribute to an understanding of plant and crop growth in space.

Follow @ISS_Research on Twitter for more information about the science happening on space station. 

Watch the launch live HERE on Nov. 11, liftoff is scheduled for 7:37 a.m. EDT!

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

Anonymous asked:

What is the best about being mission control?

Science in Space!

What science is headed to the International Space Station with Orbital ATK’s cargo resupply launch? From investigations that study magnetic cell culturing to crystal growth, let’s take a look…

Orbital ATK is targeted to launch its Cygnus spacecraft into orbit on April 18, delivering tons of cargo, supplies and experiments to the crew onboard.

Efficacy and Metabolism of Azonafide Antibody-Drug Conjugates in Microgravity Investigation

In microgravity, cancer cells grow in 3-D. Structures that closely resemble their form in the human body, which allows us to better test the efficacy of a drug. This experiment tests new antibody drug conjugates.

These conjugates combine an immune-activating drug with antibodies and target only cancer cells, which could potentially increase the effectiveness of chemotherapy and potentially reduce the associated side-effects. Results from this investigation could help inform drug design for cancer patients, as well as more insight into how microgravity effects a drug’s performance.

Genes in Space

The Genes in Space-2 experiment aims to understand how the regulation of telomeres (protective caps on the tips of chromosomes) can change during spaceflight. Julian Rubinfien, 16-year-old DNA scientist and now space researcher, is sending his experiment to space as part of this investigation. 

3-D Cell Culturing in Space

Cells cultured in space spontaneously grow in 3-D, as opposed to cells cultured on Earth which grow in 2-D, resulting in characteristics more representative of how cells grow and function in living organisms. The Magnetic 3-D Cell Culture for Biological Research in Microgravity investigation will test magnetized cells and tools that may make it easier to handle cells and cell cultures.

This could help investigators improve the ability to reproduce similar investigations on Earth.

SUBSA

The Solidification Using a Baffle in Sealed Ampoules (SUBSA) investigation was originally operated successfully aboard the space station in 2002. 

Although it has been updated with modernized software, data acquisition, high definition video and communications interfaces, its objective remains the same: advance our understanding of the processes involved in semiconductor crystal growth. 

Space Debris

Out-of-function satellites, spent rocket stages and other debris frequently reenter Earth’s atmosphere, where most of it breaks up and disintegrates before hitting the ground. However, some larger objects can survive. The Thermal Protection Material Flight Test and Reentry Data Collection (RED-Data2) investigation will study a new type of recording device that rides alongside of a spacecraft reentering the Earth’s atmosphere. Along the way, it will record data about the extreme conditions it encounters, something scientists have been unable to test on a large scale thus afar.

Understanding what happens to a spacecraft as it reenters the atmosphere could lead to increased accuracy of spacecraft breakup predictions, an improved design of future spacecraft and the development of materials that can resist the extreme heat and pressure of returning to Earth. 

IceCube CubeSat

IceCube, a small satellite known as a CubeSat, will measure cloud ice using an 883-Gigahertz radiometer. Used to predict weather and climate models, IceCube will collect the first global map of cloud-induced radiances. 

The key objective for this investigation is to raise the technology readiness level, a NASA assessment that measures a technology’s maturity level.

Advanced Plant Habitat

Joining the space station’s growing list of facilities is the Advanced Plant Habitat, a fully enclosed, environmentally controlled plant habitat used to conduct plant bioscience research. This habitat integrates proven microgravity plant growth processes with newly-developed technologies to increase overall efficiency and reliability. 

The ability to cultivate plants for food and oxygen generation aboard the space station is a key step in the planning of longer-duration, deep space missions where frequent resupply missions may not be a possibility.

Watch Launch!

Orbital ATK and United Launch Alliance (ULA) are targeting Tuesday, April 18 for launch of the Cygnus cargo spacecraft to the International Space Station. Liftoff is currently slated for 11 a.m. EST.

Watch live HERE.

You can also watch the launch live in 360! This will be the world’s first live 360-degree stream of a rocket launch. Watch the 360 stream HERE.

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

The Moon in Motion

Happy New Year! And happy supermoon! Tonight, the Moon will appear extra big and bright to welcome us into 2018 – about 6% bigger and 14% brighter than the average full Moon. And how do we know that? Well, each fall, our science visualizer Ernie Wright uses data from the Lunar Reconnaissance Orbiter (LRO) to render over a quarter of a million images of the Moon. He combines these images into an interactive visualization, Moon Phase and Libration, which depicts the Moon at every day and hour for the coming year. 

Want to see what the Moon will look like on your birthday this year? Just put in the date, and even the hour (in Universal Time) you were born to see your birthday Moon.

Our Moon is quite dynamic. In addition to Moon phases, our Moon appears to get bigger and smaller throughout the year, and it wobbles! Or at least it looks that way to us on Earth. This wobbling is called libration, from the Latin for ‘balance scale’ (libra). Wright relies on LRO maps of the Moon and NASA orbit calculations to create the most accurate depiction of the 6 ways our Moon moves from our perspective.

1. Phases

The Moon phases we see on Earth are caused by the changing positions of the Earth and Moon relative to the Sun. The Sun always illuminates half of the Moon, but we see changing shapes as the Moon revolves around the Earth. Wright uses a software library called SPICE to calculate the position and orientation of the Moon and Earth at every moment of the year. With his visualization, you can input any day and time of the year and see what the Moon will look like!

2. Shape of the Moon

Check out that crater detail! The Moon is not a smooth sphere. It’s covered in mountains and valleys and thanks to LRO, we know the shape of the Moon better than any other celestial body in the universe. To get the most accurate depiction possible of where the sunlight falls on the lunar surface throughout the month, Wright uses the same graphics software used by Hollywood design studios, including Pixar, and a method called ‘raytracing’ to calculate the intricate patterns of light and shadow on the Moon’s surface, and he checks the accuracy of his renders against photographs of the Moon he takes through his own telescope.

3. Apparent Size 

The Moon Phase and Libration visualization shows you the apparent size of the Moon. The Moon’s orbit is elliptical, instead of circular - so sometimes it is closer to the Earth and sometimes it is farther. You’ve probably heard the term “supermoon.” This describes a full Moon at or near perigee (the point when the Moon is closest to the Earth in its orbit). A supermoon can appear up to 14% bigger and brighter than a full Moon at apogee (the point when the Moon is farthest from the Earth in its orbit). 

Our supermoon tonight is a full Moon very close to perigee, and will appear to be about 14% bigger than the July 27 full Moon, the smallest full Moon of 2018, occurring at apogee. Input those dates into the Moon Phase and Libration visualization to see this difference in apparent size!

4. East-West Libration

Over a month, the Moon appears to nod, twist, and roll. The east-west motion, called ‘libration in longitude’, is another effect of the Moon’s elliptical orbital path. As the Moon travels around the Earth, it goes faster or slower, depending on how close it is to the Earth. When the Moon gets close to the Earth, it speeds up thanks to an additional pull from Earth’s gravity. Then it slows down, when it’s farther from the Earth. While this speed in orbital motion changes, the rotational speed of the Moon stays constant. 

This means that when the Moon moves faster around the Earth, the Moon itself doesn’t rotate quite enough to keep the same exact side facing us and we get to see a little more of the eastern side of the Moon. When the Moon moves more slowly around the Earth, its rotation gets a little ahead, and we see a bit more of its western side.

5. North-South Libration

The Moon also appears to nod, as if it were saying “yes,” a motion called ‘libration in latitude’. This is caused by the 5 degree tilt of the Moon’s orbit around the Earth. Sometimes the Moon is above the Earth’s northern hemisphere and sometimes it’s below the Earth’s southern hemisphere, and this lets us occasionally see slightly more of the northern or southern hemispheres of the Moon! 

6. Axis Angle

Finally, the Moon appears to tilt back and forth like a metronome. The tilt of the Moon’s orbit contributes to this, but it’s mostly because of the 23.5 degree tilt of our own observing platform, the Earth. Imagine standing sideways on a ramp. Look left, and the ramp slopes up. Look right and the ramp slopes down. 

Now look in front of you. The horizon will look higher on the right, lower on the left (try this by tilting your head left). But if you turn around, the horizon appears to tilt the opposite way (tilt your head to the right). The tilted platform of the Earth works the same way as we watch the Moon. Every two weeks we have to look in the opposite direction to see the Moon, and the ground beneath our feet is then tilted the opposite way as well.

So put this all together, and you get this:

Beautiful isn’t it? See if you can notice these phenomena when you observe the Moon. And keep coming back all year to check on the Moon’s changing appearance and help plan your observing sessions.

Follow @NASAMoon on Twitter to keep up with the latest lunar updates. 

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.

The Past, Present and Future of Exploration on Mars

Today, we’re celebrating the Red Planet! Since our first close-up picture of Mars in 1965, spacecraft voyages to the Red Planet have revealed a world strangely familiar, yet different enough to challenge our perceptions of what makes a planet work.

You’d think Mars would be easier to understand. Like Earth, Mars has polar ice caps and clouds in its atmosphere, seasonal weather patterns, volcanoes, canyons and other recognizable features. However, conditions on Mars vary wildly from what we know on our own planet.

Join us as we highlight some of the exploration on Mars from the past, present and future:

PAST

Viking Landers

Our Viking Project found a place in history when it became the first U.S. mission to land a spacecraft safely on the surface of Mars and return images of the surface. Two identical spacecraft, each consisting of a lander and an orbiter, were built. Each orbiter-lander pair flew together and entered Mars orbit; the landers then separated and descended to the planet’s surface.

Besides taking photographs and collecting other science data, the two landers conducted three biology experiments designed to look for possible signs of life.

Pathfinder Rover

In 1997, Pathfinder was the first-ever robotic rover to land on the surface of Mars. It was designed as a technology demonstration of a new way to deliver an instrumented lander to the surface of a planet. Mars Pathfinder used an innovative method of directly entering the Martian atmosphere, assisted by a parachute to slow its descent and a giant system of airbags to cushion the impact.

Pathfinder not only accomplished its goal but also returned an unprecedented amount of data and outlived its primary design life.

PRESENT

Spirit and Opportunity

In January 2004, two robotic geologists named Spirit and Opportunity landed on opposite sides of the Red Planet. With far greater mobility than the 1997 Mars Pathfinder rover, these robotic explorers have trekked for miles across the Martian surface, conducting field geology and making atmospheric observations. Carrying identical, sophisticated sets of science instruments, both rovers have found evidence of ancient Martian environments where intermittently wet and habitable conditions existed.

Both missions exceeded their planned 90-day mission lifetimes by many years. Spirit lasted 20 times longer than its original design until its final communication to Earth on March 22, 2010. Opportunity continues to operate more than a decade after launch.

Mars Reconnaissance Orbiter

Our Mars Reconnaissance Orbiter left Earth in 2005 on a search for evidence that water persisted on the surface of Mars for a long period of time. While other Mars missions have shown that water flowed across the surface in Mars’ history, it remained a mystery whether water was ever around long enough to provide a habitat for life.

In addition to using the rover to study Mars, we’re using data and imagery from this mission to survey possible future human landing sites on the Red Planet.

Curiosity

The Curiosity rover is the largest and most capable rover ever sent to Mars. It launched November 26, 2011 and landed on Mars on Aug. 5, 2012. Curiosity set out to answer the question: Did Mars ever have the right environmental conditions to support small life forms called microbes? 

Early in its mission, Curiosity’s scientific tools found chemical and mineral evidence of past habitable environments on Mars. It continues to explore the rock record from a time when Mars could have been home to microbial life.

FUTURE

Space Launch System Rocket

We’re currently building the world’s most powerful rocket, the Space Launch System (SLS). When completed, this rocket will enable astronauts to begin their journey to explore destinations far into the solar system, including Mars.

Orion Spacecraft

The Orion spacecraft will sit atop the Space Launch System rocket as it launches humans deeper into space than ever before. Orion will serve as the exploration vehicle that will carry the crew to space, provide emergency abort capability, sustain the crew during the space travel and provide safe re-entry from deep space return velocities.

Mars 2020

The Mars 2020 rover mission takes the next step in exploration of the Red Planet by not only seeking signs of habitable conditions in the ancient past, but also searching for signs of past microbial life itself.

The Mars 2020 rover introduces a drill that can collect core samples of the most promising rocks and soils and set them aside in a “cache” on the surface of Mars. The mission will also test a method for producing oxygen from the Martian atmosphere, identify other resources (such as subsurface water), improve landing techniques and characterize weather, dust and other potential environmental conditions that could affect future astronauts living and working on the Red Planet.

For decades, we’ve sent orbiters, landers and rovers, dramatically increasing our knowledge about the Red Planet and paving the way for future human explorers. Mars is the next tangible frontier for human exploration, and it’s an achievable goal. There are challenges to pioneering Mars, but we know they are solvable. 

To discover more about Mars exploration, visit: https://www.nasa.gov/topics/journeytomars/index.html

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

Our New Satellite to Study the Edge of Space

We're about to launch a new satellite called ICON — the Ionospheric Connection Explorer — to study our planet's boundary to space.

The overlap between Earth's upper atmosphere and outer space is complicated and constantly changing. It's made up of a mix of neutral gas (like the air we breathe) and charged particles, where negatively charged electrons have separated from positively charged ions. This charged particle soup reacts uniquely to the changing electric and magnetic fields in near-Earth space, while weather conditions from here on Earth can also travel upwards and influence this region. This makes Earth's interface to space a dynamic, hard-to-predict region of the atmosphere.

Understanding what causes the changes in this region and how to predict them isn't just a matter of curiosity. Earth's boundary to space is home to many of our Earth-orbiting satellites, and it also plays a role in transmitting signals for communications and navigation systems. Unpredictable changes here can garble those signals and even shorten the lifetime of satellites.

ICON, launching on Nov. 7, will study this region with a unique combination of instruments. Orbiting about 360 miles above Earth, ICON will use its cameras to measure winds near the upper edge of Earth’s boundary to space and track atmospheric composition and temperature by studying a phenomenon called airglow. ICON also carries an instrument that will capture and measure the particles directly around the spacecraft, or in situ. 

ICON is launching aboard a Northrop Grumman Pegasus XL rocket. On launch day, the Pegasus XL is carried out over the ocean by Northrop Grumman's L-1011 Stargazer aircraft, which takes off from Cape Canaveral Air Force Station in Florida. About 50 miles off the coast of Florida, the Pegasus XL drops from the plane and free-falls for about five seconds before igniting and carrying ICON into low-Earth orbit.

NASA TV coverage of the launch starts at 2:45 a.m. EST on Nov. 7 at nasa.gov/live. You can also follow along with the mission on Twitter, Facebook or at nasa.gov/icon.

Everything You Need to Know About the Aug. 21 Eclipse

On Aug. 21, all of North America will experience a solar eclipse.

If skies are clear, eclipse-watchers will be able to see a partial solar eclipse over several hours, and some people – within the narrow path of totality – will see a total solar eclipse for a few moments.

How to Watch

It’s never safe to look at the Sun, and an eclipse is no exception. During a partial eclipse (or on any regular day) you must use special solar filters or an indirect viewing method to watch the Sun.

If you have solar viewing glasses, check to make sure they’re safe and undamaged before using them to look at the Sun. Make sure you put them on before looking up at the Sun, and look away before removing them. Eclipse glasses can be used over your regular eyeglasses, but they should never be used when looking through telescopes, binoculars, camera viewfinders, or any other optical device.

If you don’t have eclipse glasses, you can still watch the eclipse indirectly! You can make a pinhole projector out of a box, or use any other object with tiny holes – like a piece of cardstock with a hole, or your outstretched, interlaced fingers – to project an image of the partially eclipsed Sun onto the ground.

Of course, if it’s cloudy (or you’d just rather stay inside), you can watch the whole thing online with us at nasa.gov/eclipselive. Tune in starting at noon ET.

If you’re in the path of totality, there will be a few brief moments when it is safe to look directly at the eclipse. Only once the Moon has completely covered the Sun and there is no light shining through is it safe to look at the eclipse. Make sure you put your eclipse glasses back on or return to indirect viewing before the first flash of sunlight appears around the Moon’s edge.

Why do eclipses happen?

A solar eclipse happens when the Moon passes directly between the Sun and Earth, casting its shadow down on Earth’s surface. The path of totality – where the Moon completely covers the Sun – is traced out by the Moon’s inner shadow, the umbra. People within the Moon’s outer shadow, the penumbra, can see a partial eclipse.

The Moon’s orbit around Earth is tilted by about five degrees, meaning that its shadow usually doesn’t fall on Earth. Only when the Moon lines up exactly between the Sun and Earth do we see an eclipse.

Though the Sun is about 400 times wider than the Moon, it is also about 400 times farther away, making their apparent sizes match up almost exactly. This is what allows the Moon to block out the Sun’s bright face, while revealing the comparatively faint, pearly-white corona.

The Science of Eclipses

Eclipses are a beautiful sight to see, and they’re also helpful for our scientists, so we’re funding eleven ground-based science investigations to learn more about the Sun and Earth.

Total solar eclipses reveal the innermost regions of the Sun’s atmosphere, the corona. Though it’s thought to house the processes that kick-start much of the space weather that can influence Earth, as well as heating the whole corona to extraordinarily high temperatures, we can’t study this region at any other time. This is because coronagraphs – the instruments we use to study the Sun’s atmosphere by creating artificial eclipses – must cover up much of the corona, as well as the Sun’s face in order to produce clear images.

Eclipses also give us the chance to study Earth’s atmosphere under uncommon conditions: the sudden loss of solar radiation from within the Moon’s shadow. We’ll be studying the responses of both Earth’s ionosphere – the region of charged particles in the upper atmosphere – and the lower atmosphere.

Learn all about the Aug. 21 eclipse at eclipse2017.nasa.gov, and follow @NASASun on Twitter and NASA Sun Science on Facebook for more. Watch the eclipse through the eyes of NASA at nasa.gov/eclipselive starting at 12 PM ET on Aug. 21. 

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

Solar System: Be in the Know This Week

Our solar system is huge, let us break it down for you. Here are a few things to know this week:

1. Say Farewell to a Comet Rider

After a successful and eventful adventure landing on a comet, no more signals will be received from the Rosetta mission's comet lander, Philae.

Send your goodbyes to Philae

2. Target Shooting

Using new software our very own Mars rover Curiosity can even choose its own rock targets for its laser spectrometer. 

Find out how Curiosity selects its own targets

3. Flares for the Dramatic

Our sun recently emitted three mid-size solar flares, and the Solar Dynamics Observatory captured it all.  

Watch the Show!

4. Bring the Heat

Jupiter's Great Red Spot may be the mysterious heat source behind the planet’s surprisingly high upper atmospheric temperatures. When Juno begins its science orbits, the Great Red Spot will be among its top targets.

Learn More

5. Cut and Dried

The gullies on today’s Red Planet were not cut by flowing liquid water, as previously thought, but rather by processes such as the freeze and thaw of carbon dioxide frost. New findings using data from our Mars Reconnaissance Orbiter provide a new picture of the cause,

Learn More

Discover the full list of 10 things to know about our solar system this week HERE.

Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com

Photograph of the Apollo 13 Spacecraft Being Returned to the Prime Recovery Ship, USS Iwo Jima, 4/17/1970

Series: Color Photograph Files, 1965 - 2002. Record Group 255: Records of the National Aeronautics and Space Administration, 1903 - 2006. 

Apollo 13 was intended to be the third Apollo mission to land on the Moon. The craft was launched from Kennedy Space Center in Merritt Island, Florida on April 11, 1970. Two days into the flight, damaged wire insulation inside the oxygen tank in the service module ignited, causing an explosion which vented the oxygen tank into space. Without oxygen, the service module became inoperable and the lunar mission quickly turned into a mission to safely return the crew to Earth. The astronauts worked with Mission Control to shut down the command module in order to conserve the remaining oxygen, forcing all three astronauts into the lunar module. The astronauts continued to work with Mission Control to combat one technical failure after another until, on April 17, 1970, the crew landed safely in the South Pacific Ocean.

source: phillyarchives.tumblr.com